Lung hyperinflation in airway obstruction

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Lung hyperinflation in airway obstruction.

*Dept di Science Motorie, University of Genova, I-16132 Genova, Italy. +Division de Pneumologie, Centre Hospitalier Universitaire Vaudois, CH-1011 Lausanne, Switzerland. Since the early studies with inert gas dilution techniques, it has been known that residual volume and functional residual capacity are increased in patients with pulmonary emphysema [1] or acute asthma [2]. These findings were...

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Lung hyperinflation and flow limitation in chronic airway obstruction.

We reasoned that if flow limitation plays an important role in lung hyperinflation, then bronchodilatation should be associated with a decrease of functional residual capacity (FRC) only in subjects breathing under conditions of flow limitation. This hypothesis was tested in 33 subjects with chronic airway narrowing due to asthma or chronic obstructive pulmonary disease (COPD). Flow limitation ...

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Lung hyperinflation and its reversibility in patients with airway obstruction of varying severity.

The natural history of lung hyperinflation in patients with airway obstruction is unknown. In particular, little information exists about the extent of air trapping and its reversibility to bronchodilator therapy in those with mild airway obstruction. We completed a retrospective analysis of data from individuals with airway obstruction who attended our pulmonary function laboratory and had ple...

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Lung hyperinflation, perception of bronchoconstriction and airway hyperresponsiveness.

PURPOSE To compare the influence of underlying airway inflammation and lung hyperinflation on dyspnea during induced bronchoconstriction in subjects with mild asthma (or asymptomatic airway hyperresponsiveness (AAHR). METHODS Fourteen mild asthmatic and 14 AAHR subjects had methacholine and 5'-adenosine monophosphate (AMP) challenges, and induced sputum analysis. Changes in inspiratory capaci...

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Airway obstruction, dynamic hyperinflation, and breathing pattern during incremental exercise in COPD patients

Ventilatory capacity is reduced in chronic obstructive pulmonary disease (COPD) patients. Tidal volume (V T) is lower and breathing frequency higher at a given ventilation (V E) compared to healthy subjects. We examined whether airflow limitation and dynamic hyperinflation in COPD patients were related to breathing pattern. An incremental treadmill exercise test was performed in 63 COPD patient...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 1996

ISSN: 0000-0000,0903-1936

DOI: 10.1183/09031936.96.09122440